CJC-1295 (No DAC)

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CJC-1295 (No DAC)

CJC-1295 (No DAC) is a synthetic Growth Hormone–Releasing Hormone (GHRH) analog designed to stimulate the pituitary gland to naturally increase growth hormone (GH) and IGF-1 production.

Unlike the DAC (Drug Affinity Complex) version, the No DAC formula provides short, precise pulses of GH release, allowing for controlled timing, greater frequency, and more natural hormone rhythm.

This peptide is widely studied for its potential in anti-aging, muscle recovery, fat metabolism, and cellular regeneration, making it a key component in growth hormone optimization research.

Form & Stability

All Peptide Labs peptides are produced with 99%+ purity and lyophilized to preserve potency and stability.

Unmixed (Freeze-Dried): Stable for up to 1 year in the refrigerator (2–8 °C / 36–46 °F) and over 5 years in the freezer (−20 °C / −4 °F).
After Reconstitution: Store in the refrigerator (2–8 °C / 36–46 °F) and use within 30 days for optimal results.

Research Overview

1. Growth Hormone Release & Regulation

CJC-1295 (No DAC) binds to GHRH receptors in the pituitary gland, promoting natural growth hormone secretion in short, controlled pulses. This helps mimic the body’s natural GH rhythm, enhancing overall balance and hormonal responsiveness.

2. Increased IGF-1 Production

The peptide boosts the production of Insulin-Like Growth Factor-1 (IGF-1), which supports muscle repair, cellular regeneration, and metabolic function. Elevated IGF-1 levels play a crucial role in tissue recovery and anti-aging benefits.

3. Fat Loss & Lean Muscle Support

By improving GH and IGF-1 levels, CJC-1295 (No DAC) enhances lipolysis (fat breakdown) while promoting muscle protein synthesis and cellular repair, leading to improved body composition.

4. Skin, Hair, & Collagen Rejuvenation

Research shows GH and IGF-1 influence collagen production, skin elasticity, and cell turnover. CJC-1295 (No DAC) supports these regenerative processes for improved skin tone, texture, and overall vitality.

5. Sleep Quality & Recovery

CJC-1295 (No DAC) is associated with improved REM sleep and recovery efficiency, supporting muscle repair and energy balance through deep, restorative sleep cycles.

6. Synergy with Ipamorelin & Other Peptides

When combined with Ipamorelin, CJC-1295 (No DAC) enhances both frequency and magnitude of GH release without overstimulating the endocrine system — a gold-standard pairing for growth, recovery, and performance.

Storage & Stability Instructions

All Peptide Labs products are manufactured using a lyophilization (freeze-drying) process to ensure maximum stability and purity. This method allows peptides to remain 100% stable for up to 3–4 months during shipping and storage at room temperature. Once reconstituted (mixed with bacteriostatic water), peptides must be stored in the refrigerator to maintain potency and freshness. After reconstitution, peptides remain stable for up to 30 days when properly refrigerated.

What is Lyophilization?

Lyophilization is a specialized dehydration technique where peptides are frozen and exposed to low pressure, causing water to sublimate directly from solid to vapor. This process leaves behind a stable, crystalline white powder that preserves the integrity of the peptide until it’s mixed with bacteriostatic water. Short-Term Storage:

Store at room temperature if used within a few weeks.
Keep peptides cool, dry, and protected from light.
For short-term storage (days to weeks), refrigeration at under 4 °C (39 °F) is recommended.

Long-Term Storage: For longer preservation (several months to years), store peptides in a freezer at −80 °C (−112 °F). This ensures maximum stability and prevents degradation over time. (DO NOT RECONSTITUTE)

Molecular Structure

Sequence: Tyr-Ala-Asp-Ala-Ile-Phe-Thr-Asn-Ser-Tyr-Arg-Lys-Val-Leu-Gly-Gln-Leu-Ser-Ala-Arg-Lys-Leu-Leu-Gln-Asp-Ile-Met-Ser-Arg-Gln-Gln-Gly-Gly-Gly-Gly-Ser-Ala-Arg-Ala-Arg-Leu-NH₂
Molecular Formula: C₁₅₂H₂₅₂N₄₄O₄₂
Molecular Weight: 3357.91 g/mol
Form: Lyophilized (freeze-dried) powder for maximum stability